Journal of Pharmacobio-Dynamics
Online ISSN : 1881-1353
Print ISSN : 0386-846X
ISSN-L : 0386-846X
INTERACTION BETWEEN QUERCETIN AND SUPEROXIDE RADICALS. REDUCTION OF THE QUERCETIN MUTAGENICITY
IKUKO UENOMASAHIRO KOHNOKIMIE HARAIKAWAIWAO HIRONO
著者情報
キーワード: flavonoid
ジャーナル フリー

1984 年 7 巻 11 号 p. 798-803

詳細
抄録
Interaction between quercetin and superoxide radicals was investigated using xanthine-xanthine oxidase system and potassium superoxide as superoxide radical generators. Superoxide radical scavenging action of quercetin was demonstrated by measurement of the electron spin resonance spectrum of the 5-hydroperoxy-2, 2-dimethyl-1-1pyrrolidinyloxyl adduct. Degradation of quercetin by the radicals was demonstrated spectrophotometrically. Reduction of the quercetin mutagenicity by the radicals was demonstrated in the Salmonella typhimurium strain TA 98 by the Ames test.
著者関連情報
© The Pharmaceutical Society of Japan
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