Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
Structures of Mefenamic Acid Metabolites from Human Urine
Juichi SATO, Yoshinori YAMANE, Keiji ITO, Hideo BANDO
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Keywords: mefenamic acid, human urine, metabolite, glucuronide
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1993 Volume 16 Issue 8 Pages 811-812

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Abstract
Three major metabolites of mefenamic acid were isolated from the urine of a normal adult man receiving mefenamic acid orally. The structures of those metabolites were determined as glucuronides of mefenamic acid, its hydroxymethyl derivative, and its carboxylic acid derivative on the basis of spectral data.
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© The Pharmaceutical Society of Japan
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