Abstract
The effects of ethanolamine on injured liver were investigated by oral administration of ethanolamine to male ddY mice 24h after carbon tetrachloride (CCl4) injection. The serum aminotransferase activities in mice with liver injury were reduced by ethanolamine treatment (10-30mg/kg body weight). Drastically increased regerative reaction of ethanolamine treated-CCl4 injured liver was also observed through an increase in 5-bromo-2'-deoxyuridine uptake. ATP concentration in liver tissue was recovered by administration of ethanolamine. These results suggest that oral administration of ethanolamine accelerates recovery from CCl4-in-duced liver injury.
