Enzymatic Formation of 2, 3-Diaminopropionic Acid, the Direct Precursor of the Neurotoxin β-ODAP, in Lathyrus sativus

Abstract

The enzymatic breakdown of β-(isoxazolin-5-on-2-yl)-L-alanine (BIA) with formation of 2, 3-diaminopropionic acid (DAPA), the direct precursor of the neurotoxin β-ODAP in Lathyrus sativus, was confirmed in vitro. Some properties of the enzyme responsible for the biosynthesis of DAPA are described.