Biomedical Research on Trace Elements
Online ISSN : 1880-1404
Print ISSN : 0916-717X
ISSN-L : 0916-717X
冨田 寛田中 真琴生井 明浩
ジャーナル フリー

2007 年 18 巻 1 号 p. 54-62


1. In Japan, patients with taste disorder as a primary symptom of zinc deficiency are increasing.
2. The incidence of taste disorder due to diet (insufficient intake of zinc) is especially high. The serum zinc value in patients with taste disorder due to diet was 20μg/dl (in many cases mean value is 60-79μg/dl )lower than the healthy group, but the half cases remained in more than 80μg/dl.
3. The efficacy of oral administration of zinc in patients with taste disorder due to diet did not correlate with the zinc value before this therapy, but about 85%.
4. Increasing rate of serum zinc values after the oral zinc therapy in patients with taste disorder due to diet was significantly high more than the placebo group. Lower serum zinc values in the patients were more effective. Correlate with the amount of oral administration of zinc.
5. We would like to propose 80μg/dl as the diagnosis value(cutoff value) of zinc deficiency, referring to the above results and the conclusion of the Yokoi's study(Association between plasma zinc concentrations and zinc kinetic parameters in premenopausal women).

© 2007 一般社団法人 日本微量元素学会
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