MECHANISM OF ANTITUMOR ACTION OF POLYSACCHARIDE FRACTION PREPARED FROM BAGASSE. I
1967 年 58 巻 1 号 p. 1-4
詳細
1967 年 58 巻 1 号 p. 1-4
The antitumor effect of a polysaccharide fraction isolated from bagasse (crushed residue of sugar cane after pressing out the juice) has been tested against sarcoma-180 subcutaneously implanted in mice and the effect was found to be just as marked as that of similar fraction from bamboo leaves. The most significant results were obtained with 100mg/kg doses.
In continued attempts to elucidate the mechanism of this kind of host-mediated antitumor action of the bagasse polysaccharide, the properties of plasma protein was compared between the polysaccharide-treated and normal control mice. There was a considerable increase in circulating protein especially globulin fraction, in the treated mice.
Effect on plasma protein of certain other plant polysaccharides without antitumor effect was determined in the same way as in the case of the bagasse polysaccharide.
