Abstract
Provision of early hemodynamic and oxygen transport resuscitation is one of the key components to improve outcome of the septic shock patients. Since year 2001, importance of achieving a goal in a context of early, quantitative goal-directed therapy(EGDT) has been implicated. Prompt administration of crystalloids such as Ringer's solutions by 30 ml/kg or 2,000 ml, in combination with vasopressors represented by noradrenaline, with referring mean arterial blood pressure and arterial lactate level has been accepted as a useful treatment option. Controversy exists, however, regarding the type of fluids, utilization of universal algorism including other hemodynamic parameters, or vasopressors/inotropes. Avoidance of excess fluid administration is also currently debated. This concise review will discuss current evidence on the aforementioned controversies.
