CHEMOTHERAPY
Online ISSN : 1884-5894
Print ISSN : 0009-3165
ISSN-L : 0009-3165
ブドウ球菌の酸性フォスファターゼに関する研究
波多間 幸信
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ジャーナル フリー

1968 年 16 巻 3 号 p. 349-358

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About 100 strains of Staphylococci were isolated from patients and the quantity of acid phosphatase '(A-Pase) as well as the biochemical activities were studied. Furthermore, the relationships of A-Pase activity and the pathogenicity or virulence to animals were examined, obtaining the results as fo llows:
1) The quantitative method of A-Pase activity modified by the author seemed to correlate we ll with other qualitative method. Moreover, the author's method is superior to others because it can be m easured quantitatively.
2) C oagulase activities of Staphylococci correlate well with A-Pase activities. Furthermore, A-Pase activity has intimate relationship with pathogenicity.
3) Strains of high A-Pase have show n strong mannit decomposition activities.
4) Strains of 80/81 phage type have produced more A-Pase than those of other phage type.
5) Strains of high A-Pase activity have shown light blue or yellow colonies on crystal v iolet media, on the other hand strains of low A-Pase wite colonies.
6) Strains of high A-Pase have shown shown strong hemolysis.
7) The amount of A-Pase correlate well with the tox icity and intracutaneous reactions to mice. From these results, A-Pase activities of Staphylococci correlate well with the characteristics w hich have relationships to the pathogenicity. Therefore, it is recommended that A-Pase activities, together with coagulase, should be examined for the identification of pathogenic Staphylococci.
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