Sulfamethoxazole-Trimethoprim合剤に関する2, 3の実験
1973 年 21 巻 2 号 p. 351-353
詳細
1973 年 21 巻 2 号 p. 351-353
The growth inhibitory activity of sulfamethoxazole (SMX) against Escherichia coli in vitro was potentiated by the addition of trimethoprim (TMP). The growth inhibitory activity (Escherichia coli) of sera of a patient following oral administration of SMX-TMP combination product was similar to that of the same patient after a dose of SMX alone. However, the effect of the sera on Escherichia coli reproduction curve was more potent with those following administration of SMX-TMP combination product than with those after SMX alone, indicating potentiation of the bactericidal activity by the combination.
