Sulfamethoxazole-Trimethoprim合剤の併用効果についての検討
1973 年 21 巻 2 号 p. 354-356
詳細
1973 年 21 巻 2 号 p. 354-356
1. Antimicrobial activities in vitro : The effect of combination treatment with SMX and TMP against Staphylococcus aureus and Escherichia coli was remarkable.
2. Experimental treatment of Staphylococcus infection in mice : Effective results of combination treatment with SMX and TMP were obtained, but its effect was weak compared with in vitro studies.
3. Serum antimicrobial activity test (SAAT) : The level of SAAT in the single treatment with SMX as well as the combination treatment with SMX and TMP was low of less than four times.
4. Clinical results : Effective results were obtained in five cases out of thirteen cases of chronic respiratory infection treated with ST drugs.
