1) Cefatrizine was administered to 45 patients with urinary tract infections and acute gonorrhea consisting of out- and in-patients of Department of Urology, Kyushu University and Sanshinkai Hara Hospital. Since 8 patients were dropouted, 37 were subject to the evaluation.
2) Three of 7 patients with simple urinary tract infections were administered 500 mg daily, and other patients with urinary tract infections were given 1, 000 mg daily. Out of the patients with acute gonorrhea, 3 patients were administered 1, 000 mg daily, 11 were given 1, 500 mg daily and 3 were given 2, 000 mg daily.
3) Seven patients with simple urinary tract infections resulted in 2 excellent and 5 good with effectiveness rate of 100%. Thirteen patients with complicated urinary tract infections resulted in 2 excellent, 4 good and 7 poor with effectiveness rate of 46%. In acute gonorrhea 10 patients were excellent and 7 were good.
4) Nausea was noted in 7 patients out of whom one patient was discontinued the medication, although the nausea disappeared after the discontinuation.
5) Although the resistant strains would appear in future, cefatrizine may be considered as a useful drug for the treatment of urinary tract infections and acute gonorrhea.
