Abstract
1. Relations between the fluorine contents of the animal body, drinking water, and feedstuffs, and chronic fluorine poisoning were studied by determining the fluorine contents in them.
2. It was found that fluorine contents were higher in bones than in teeth, and in cattle than in horses.
3. The fluorine contents of teeth, bones, and hairs of cattle raised in hi h-fluorine areas were 2 to 10 times, 2 to 10 times, and 2 to 5 times, respectively, as high as those in low-fluorine areas. Thsre was no difference in fluorine content among the blood, liver, muscles, and milk.
4. In high-fluorine areas, such as the Aso volcano region, the fluorine contents of bones or teeth of domestic animals with mottled teeth were 2 to 5 times as high as those of domestic animals without mottled teeth.
5. The fluorine content of drinking water in high-fluorine areas was 5 to 40 times as high as that in low-fluorine areas, but there was no difference in fluorine content with regard to feedstuffs.
6. When fluorine was administered to rats and rabbits, the fluorine contents of bones and teeth were 5 to 8 times, and those of hairs, blood, heart, spleen, brain, and muscles were about 2 times as high as those in normal animals. Thre was no difference, however, in fluorine content with regard to the liver, kidney, and lung.
