1964 Volume 35 Issue 6 Pages 322-328
To clarify the inheritance of the serological constitution of domestic animals, it is very important to research into that of their antibodies. The heritable mode of anti-Q agglutinin in human serum has already been reported to be Mendelian recessive.
Present experiment was studied on the frequency of appearance of anti-Q agglutinin in normal sera of domestic animals (1084 pigs, 152 cattle, 54 horses, 150 goats, 109 sheep and 194 rabbits). The results obtained are as follows:
1) Seventy four cases (6.83%) out of 1084 pigs possessed anti-Q agglutinin. The agglutinin titer of 10 (13.51%) out of 74 was 4 or 8 fold. The ratio of these 10 cases to 1084 was 0.92%. On the frequency of appearance of anti-Q agglutinin by the breed of pigs, Middle Yorkshire breed was 6.31% (64 cases out of 1015), Chinese pig and its hybrid 34.48% (10 out of 29) and Berkshire breed 0%.
2. One case (1.85%) out of 54 horses, 1 case (0.67%) 150 goats and 2 cases (1.03%) 194 rabbits, respectively, possessed anti-Q agglutinin; but in 152 cattle and 109 sheep anti-Q agglutinin was not present.
3. Concerning anti-Q agglutinin titers of these cases, in 74 cases of pigs, 54 cases (72.97%) were 1 fold, 10 (13.51%) 2 fold, 7 (9.64%) 4 fold and 3 (4.05%) 8 fold. One case of horse was 4 fold, and 1 case of goat and 2 cases of rabbits were 1 fold.
4. Heteroagglutinin titers of normal sera of domestic animals distributed between 0 fold and 64 fold and their mode is between 2 fold and 8 fold.
5. The correlation between the heteroagglutinin titers with red cells and the presence of anti-Q agglutinin was investigated on normal sera of 201 pigs. Anti-Q agglutinin was recognized in 10 cases (32.2%) of 16 fold of heteroagglutinin titer, 10 cases (62.5%) of 32 fold and 2 cases (100.0%) of 64 fold, but in none cases under 8 fold. Therefore, the normal sera above 16 fold of heteroagglutinin titer may be suitable for obtaining anti-Q agglutinin.
