Abstract
The effect of chlorpromazine hydrochloride(CPH) on survival and metabolism of goat and bull spermatozoa was examined. The results obtained are as follows. 1. The addition of 10 to 40mg per cent of CPH was beneficial to the survival of spermatozoa, particularly of bull spermatozoa, which stored with egg-yolk citrate buffer at 4°C. 2. CPE stimulated the oxidation of pyruvate, acetate and fructose by spermatozoa at lower levels while it inhibited the oxidative activity and motility of spermatozoa at the 10mg level. 3. CPH inhibited the anaerobic glycolysis of spermatozoa when it was added to the sperm suspension with glucose before the preliminary incubation period.
