The authors apologize for the written mistakes in the Result sections. Corrections are shown below.
1) Page 1608, right column, lines 37–38
Incorrect:
Mean initial MDZ dose was 0.29±0.19 µg/kg/h and maximum dose was 0.84±0.64 µg/kg/h.
Correct:
Mean initial MDZ dose was 0.29±0.19 µg/kg/min and maximum dose was 0.84±0.64 µg/kg/min.
2) Page 1609, Table 1
Table 1.
Baseline Characteristics
| |
Total
(n=37) |
Dexmedetomidine
(n=25) |
Midazolam
(n=12) |
P value |
| Background |
| Age (years) |
70±15 |
70±11 |
68±21 |
0.60 |
| Male sex |
29 (78%) |
21 (84%) |
8 (67%) |
0.39 |
| NYHA functional class IV |
37 (100%) |
25 (100%) |
12 (100%) |
1.00 |
| Body weight (kg) |
55.5±24.5 |
59.4±28.9 |
47.5±6.4 |
0.17 |
| Body mass index (kg/m2) |
21.1±7.0 |
22.2±8.4 |
19.1±2.3 |
0.23 |
| LVEF (%) |
24 (16, 45) |
20 (14, 40) |
35 (20, 59) |
0.10 |
| Prior HF hospitalization (times) |
4 (2, 7) |
4 (2, 6) |
6 (2, 8) |
0.16 |
| Hospitalization length (days) |
53 (28, 87) |
48 (20, 129) |
61 (32, 86) |
0.76 |
| |
| Laboratory data |
| BNP (pg/mL) |
1,180 (616, 2,734) |
1,333 (659, 2,522) |
771 (380, 2,963) |
0.32 |
| eGFR (mL/min/1.73 m2) |
18.2 (8.7, 31.7) |
18.2 (9.3, 28.3) |
17.9 (7.8, 49.1) |
0.87 |
| Creatinine (mg/dL) |
3.0 (1.8, 5.6) |
3.0 (2.0, 5.6) |
2.9 (1.1, 6.1) |
0.66 |
| Total bilirubin (mg/dL) |
1.1 (0.8, 1.7) |
1.1 (0.9, 1.8) |
0.9 (0.4, 1.3) |
0.06 |
| Albumin (g/dL) |
3.0±0.6 |
3.0±0.5 |
3.1±0.6 |
0.61 |
| Indication to sedation |
|
|
|
0.21 |
| Dyspnea |
7 (19%) |
5 (20%) |
2 (17%) |
|
| General malaise/fatigue |
19 (51%) |
14 (56%) |
5 (42%) |
|
| Delirium |
4 (11%) |
3 (12%) |
1 (8%) |
|
| Psychological distress |
3 (8%) |
0 (0%) |
3 (25%) |
|
| Pain |
3 (8%) |
2 (8%) |
1 (8%) |
|
| Others |
1 (3%) |
1 (4%) |
0 (0%) |
|
| Details of sedative agents |
| Duration of drug use (days) |
4 (2, 10) |
4 (2, 11) |
4 (2, 9) |
0.73 |
| Presence of loading |
5 (14%) |
2 (8%) |
3 (25%) |
0.30 |
| Intermittent administration |
12 (32%) |
9 (36%) |
3 (25%) |
0.71 |
| Starting dose* |
|
0.17±0.08 |
0.29±0.19 |
|
| Maximum dose* |
|
0.51±0.34 |
0.84±0.64 |
|
Continuous variables are presented as mean±standard deviation or median (interquartile range). Categorical variables are presented as number of patients (%). *Doses expressed in units of μg/kg/h for dexmedetomidine and μg/kg/min for midazolam. BNP, B-type natriuretic peptide; eGFR, estimated glomerular filtration rate; HF, heart failure; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association.
