Heart Transplantation Ameliorates Ambulation Capacity in Patients With Muscular Dystrophy　― An Analysis of 9 Cases ―

Osamu Seguchi; Kensuke Kuroda; Tomoyuki Fujita; Yuto Kumai; Seiko Nakajima; Takuya Watanabe; Masanobu Yanase; Yorihiko Matsumoto; Satsuki Fukushima; Koichi Kimura; Norihide Fukushima

doi:10.1253/circj.CJ-18-1060

This article has now been updated. Please use the final version.

Heart Transplantation Ameliorates Ambulation Capacity in Patients With Muscular Dystrophy　― An Analysis of 9 Cases ―

Osamu Seguchi, Kensuke Kuroda, Tomoyuki Fujita, Yuto Kumai, Seiko Nakajima, Takuya Watanabe, Masanobu Yanase, Yorihiko Matsumoto, Satsuki Fukushima, Koichi Kimura, Norihide Fukushima

Author information

Osamu Seguchi
Department of Transplant Medicine, National Cerebral and Cardiovascular Center
Kensuke Kuroda
Department of Transplant Medicine, National Cerebral and Cardiovascular Center
Tomoyuki Fujita
Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center
Yuto Kumai
Department of Transplant Medicine, National Cerebral and Cardiovascular Center
Seiko Nakajima
Department of Transplant Medicine, National Cerebral and Cardiovascular Center
Takuya Watanabe
Department of Transplant Medicine, National Cerebral and Cardiovascular Center
Masanobu Yanase
Department of Transplant Medicine, National Cerebral and Cardiovascular Center
Yorihiko Matsumoto
Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center
Satsuki Fukushima
Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center
Koichi Kimura
Department of Advanced Medical Science, The Institute of Medical Science, The University of Tokyo
Norihide Fukushima
Department of Transplant Medicine, National Cerebral and Cardiovascular Center

Keywords: Advanced heart failure, Ambulation, Exercise capacity, Heart transplantation, Muscular dystrophy

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Supplementary material

Article ID: CJ-18-1060

DOI https://doi.org/10.1253/circj.CJ-18-1060

The final version of this article is now available: Vol. 83 (2019), No. 3 pp. 684-686

Details

Abstract

Background: Heart transplantation (HTx) is reported to have a comparable effect on the prognosis of heart failure patients without muscular disease and for those with muscular dystrophy (MD). However, little is known about the changes in muscular diseases in patients with MD after HTx.

Methods and Results: We assessed the ambulatory capacity of 9 patients with MD who underwent HTx. All patients demonstrated improvement in ambulation to varying degrees and 1 patient successfully climbed Mount Fuji 3.8 years after HTx.

Conclusions: HTx potentially improves not only the prognosis but also the ambulatory capacity of patients with MD.

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