Japanese Circulation Journal
Print ISSN : 0047-1828
Study on the Allergic Problem of Masugi-Nephritis (II). : Nephrotoxin-Nephritis of the Rabbits which have been cured from the same disease.
M. Oue
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1949 Volume 13 Issue 1 Pages 20-22

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Abstract
When nephrotoxin is injected intravenously into the rabbits which habe been already cured from nephrotoxin-nephritis, nephritis appears on those rabbits soon after the re-inoculation. The intensity of nephritis is at its height during the following 24 hours, a reoccurence occurrs about one week later. When the normal duck serum is injected intarvenusly into the rabbits which have been cured from nephrotoxin nephritis, appears also nephritis of slight degree to them soon after, but no reoccurence occurs therafter. Now we come to the conclusion as follows : when the rabbits are sensitized previously with nephrotoxin, antibody against the duck serum contained in nephrotoxin is produced in the bodies of the rabbits, therefore nephritis appears soon (after re-inoculation of nephrotoxin, both normal anaphylaxis and anti-anaphylaxis occuring in the kidney of the rabbits.
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© 1949 Japanese Circulation Society
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