We investigated on the body types of 454 cases of hypertension and as the control 378 cases of various kinds of patients over 35 years old (excepting tuberculosis and cancer) who showed normal blood pressure. And following results were gained. 1) The patients suffering from hypertension have no characteristic body type, for instance appoplectic habit. The distribution of the body type of hypertension does not essentially differ from that of the control. And yet, as far the patients of hypertension there are a little more of the picnic type than the control, and a little less of the leptosomatic type. 2) The male patients of the essential hypertension are larger physical constitution and more nourished than those of renal hypertension. From the distribution of the body type there are more of the picnic type and less of the leptosomatic type, when we compare the former with the latter. In case of the essential hypertension are shorter of stature ond more of the picnic type than those of the renal hypertension. 3) When we compare the distribution of the body type of hereditary hypertension with that of non hereditary hypertension, it is found that the former has more the picnic type than the latter in case of male, but in female, on the contrary, the former has less of picnic type and more of leptrsomatic type than the latter. As related above, there are not so many of picnic type as believed generally up to this time.

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In the case of operation for the pulmonary tuberculosis, it must be remenbered that the heart of the patient is not always healthy. In this meaning it is very important to know the infl uence of various collapse therapies upon the heart. Results of my studies on this relation through electrocardiogram examined for 2 months after operation are as follows. Electrocardiograms of the patients suffering from pulmonary tuberculosis show 1) drop heart at 46.7%, 2) abnormality of P wave, mostly slight slip P and prolongation of P wave at 63.3%, 3) predominance of the right ventricle at 33.3% and the left at 3.3%, 4) the case in which the calculated value of P-Q interval is smaller than the observed value at 56.7%, and the pathological increase of P-Q interval is indicated at 3.3%, 5) the case in which QRS interval is prolonged as compared with normal, and "pathological increase is indicated at 6.7%, 6) the case in which the calculated value of Q-T interval is smaller than the observed value at 36.7%, and 7) myocardial damage at 83.3%. And one very serious case of them was dead soon after the Semb's thoracoplasty.

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1) After 7 years' (1936-1943) clinical experiences, the experimenter found this fact that there exists in myocarditic in a broad sense the sante painful-point on pressure as Boas' and Erwald's one in cases of gastric and doudenal ulcer. At that time of discovery, he announced, it as Fujita's point in myocarditis (1943). There exists finger-tip-signed induration of muscle or painful-point on pressure on the back, at the height of mostly third occasionally forth or fifth thoracic interspinous space. 2) Having great interests in the early disturbance of the circulatory apparatus among athletes, the experimenter examined further 22 athletes on load-test and others to prove relation between this point and heart-lung-index. Besides above mentioned myocardial painful-point on pressure, he found the same painful-point on pressure at lateral edge of vertebral body at the height of 2nd thoracic in terspinous space, which was thought to accompany turning of bronchi and lung (1st Report 1948). 3) In this report the experimenter examined 31 cases of outpatients with circuratory disturbances and ojthers of this painful-point on pressure in different seasons during 1947, and knew that in the cases of cardiac liver congestion could be proved the same painful-point on pressure at the height of 5th and 6th thoracic interspinous space.

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In the rabbits sensitized in whole bodies with the normal duckserum by the intra-(sub-) cutaneous or intraveneous injection, the dermatoreaction appears monomophically when the anti-rabbit-kidney-duck-serum is injected intra- (sub-), cutaneously to the other place from the sensitized place. I conclude that the normal anaphylactic reaction caused by the duck-serum in the anti-rabbit-kidney-duck-seum appears promptly in the injected place after the injection of the anti-rabbit-kidney-duck-serum, duplicated with the contradictory anaphylactic reaction caused by the nephrotoxin in the anti-rabbit-kidney-duck-serum.

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When nephrotoxin is injected intravenously into the rabbits which habe been already cured from nephrotoxin-nephritis, nephritis appears on those rabbits soon after the re-inoculation. The intensity of nephritis is at its height during the following 24 hours, a reoccurence occurrs about one week later. When the normal duck serum is injected intarvenusly into the rabbits which have been cured from nephrotoxin nephritis, appears also nephritis of slight degree to them soon after, but no reoccurence occurs therafter. Now we come to the conclusion as follows : when the rabbits are sensitized previously with nephrotoxin, antibody against the duck serum contained in nephrotoxin is produced in the bodies of the rabbits, therefore nephritis appears soon (after re-inoculation of nephrotoxin, both normal anaphylaxis and anti-anaphylaxis occuring in the kidney of the rabbits.

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From the old time many studies on hypertension had been done, and Goldblatt succeed for the first time experimentally to establish a persistent hypertension, which would be due to renal ischemia. On the other hand hypertension is one of the cardinal signs of the diffuse glomerulonephritis. And Masugi proved that the diffuse glomerulonephritis has its origin in allergic changes due to a antigen-antibody reaction. Maekawa thought that, if we wish to establish an allergic inflammation in any tissue or organ, we must make the antigen have affinity to that tissue or organ, and that the substance gives such affinity is cell-phosphatide. Therefore, I sensitized the rabbits with a mixture of rabbit-kidney-phospatide and fresh oxen sera, and examined clinically and histologically each organ.

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Body weight, temperature, blood picture and eye ground of the sensitized rabbits were clinically not so changed, but most of them showed ecg. lly a slight myocardial damage and a tendency of hypertension, and a persistent, relatively remarkable hypertension was observed in long lived animals, one of which showed after the secondary reinjection albuminuria, but leucocytes and erythrocytes in sediment were very little.

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The absorption of the intradermally injected eosine solution is closely related with the peripheral circulation of protein. Therefore the absorption test of eosine solution has clinical value for the study of peripheral circulation. The author measured the absorption, time of eosine solution (0.00002%, 0.1cc.) with electric photometer quantitaively, at the same time also that of salt solution. The results are as follows. 1. The absorption time of eosine solutionis in the most cases 4 to 5 haurs, its average time 4 hour and 42 minuite; 2. The absorption time of salt solution is in the most-cases 42 to 50 minuites, its average time 46.3 minuite. 3. The absorption time of eosine solution is much more delayed in comparison with that salt solution.

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