抄録
Isoproterenol was infused intravenously into subjects with lung cancer, in a search for some useful parameters for evaluation of preoperative functional cardiac reserve. The hemodynamic responses to its infusion was noted to be different in patients with and without left ventricular hypertrophy, when the cardiac output, the stroke volume, the left ventricular work and the tension-time index were concerned. It appears that the inotropic and chronotropic actions of IPR are clearly intensified in the hypertrophied heart as compared with the normal heart. The possible mechanisms of this different response are discussed in the light of this study and a review of the literature.
