HEMATOLOGICAL STUDIES ON THE SPONTANEOUSLY HYPERTENSIVE RATS WITH SPECIAL REFERENCE TO THE DEVELOPMENT OF THROMBOSIS

AKINOBU NAGAOKA; KATSUICHIRO SUDO; SHIGERU ORITA; KENZO KIKUCHI; YOSHITOMO ARAMAKI

doi:10.1253/jcj.35.11_1379

AKINOBU NAGAOKA, KATSUICHIRO SUDO, SHIGERU ORITA, KENZO KIKUCHI, YOSHITOMO ARAMAKI

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Keywords: Hypertension, Spontaneously Hypertensive Rat, Thrombosis, Platelet Aggregation, Blood Clotting

JOURNAL FREE ACCESS

1971 Volume 35 Issue 11 Pages 1379-1390

DOI https://doi.org/10.1253/jcj.35.11_1379

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Abstract

We previously reported that the occlusive thrombosis located in the hepatic vein, left atrium, and mesenteric artery was observed in the spontaneously hypertensive rats at advanced age. In this experiment, the blood clotting, platelet aggregation, and morphological and biochemical examinations of blood in the male and female hypertensive rats were performed in order to elucidate the mechanism of thrombus formation.

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