Studies on the Syntheses of Hydrogenated Quinolines and Isoquinolines as Analgesics. XII. Synthesis of N-Methyl-7-aza-des-N-morphinan (3-Methyl-5, 10b-trimethylene-1, 2, 3, 4, 4a, 5, 6, 10b-octahydrobenzo [f] isoquinoline).

抄録

The position of nitrogen in the morphinan skeleton corresponds to the 17-position of D-ring, or 7-position of the C-ring. A synthesis of the morphinan with the nitrogen in this 7-position has been described.