Abstract
Children with craniopharyngioma usually present with growth retardation and hypogonadism. They rarely develop precocious puberty. We describe here the case of a boy with craniopharyngioma who developed isosexual precocious puberty after partial surgical resection of the tumor. He was treated at first with cyproterone acetate (CA) for precocius puberty, but his bone age progressed markedly. Thus, LH-RH analog treatment was started. This regimen improved his secondary sexual development, but decreased his growth velocity from 7.2 cm/y to 2.8 cm/y. Then growth hormone treatment in addition to LHRH analog injection was started. Although the start of growth hormone (GH) treatment was delayed, his height has improved. No recurrence of the tumor has been recognized until now.
