Long-term observation of a case of localized nodular pulmonary amyloidosis

Abstract

    A 68-year-old male was diagnosed as having localized nodular pulmonary amyloidosis by open lung biopsy in 1994. Depositions of non-amyloid A type amyloid protein were detected in histochemical and immunohistochemical specimens. We have observed this patient by intermittent chest radiographs or CTs for 21 years. He has remained relatively asymptomatic except that the size and number of lung nodules have grown slowly during the period of observation. Because there are few reports of long-term observation of localized nodular pulmonary amyloidosis, this case is suggested to be worthy of report.