A patient with rheumatoid arthritis who had a delivery by caesarean section with the use of certolizumab pegol

Abstract

　We encountered a 35 year-old patient with rheumatoid arthritis (RA) who achieved delivery by caesarean section with the use of certolizumab pegol (CZP).　Caesarean section was performed because the patient had a history of enucleation of myoma uteri.　It has been reported that there is minimal placental transfer of CZP because of its Fc-free structure since the Fc part of CZP is replaced by polyethylene glycol. Like etanercept (ETN), CZP might be a desirable biological disease-modifying antirheumatic drug for RA patients who wish to give birth.