Cell Structure and Function
Online ISSN : 1347-3700
Print ISSN : 0386-7196
Hidden Peptides Encoded by Putative Noncoding RNAs
Akinobu MatsumotoKeiichi I. Nakayama
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2018 Volume 43 Issue 1 Pages 75-83

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Abstract

Although the definition of a noncoding RNA (ncRNA) is an RNA molecule that does not encode a protein, recent evidence has revealed that some ncRNAs are indeed translated to give rise to small polypeptides (usually containing fewer than 100 amino acids). Despite their small size, however, these peptides are often biologically relevant in that they are required for a variety of cellular processes. In this review, we summarize the production and functions of peptides that have been recently identified as translation products of putative ncRNAs.

Key words: long noncoding RNA (lncRNA), circular RNA (circRNA), primary miRNA (pri-miRNA), translation, peptide

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© 2018 The Author(s) CC-BY 4.0 (Submission before October 2016: Copyright © Japan Society for Cell Biology)
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