Abstract
In recent years, active pharmaceutical ingredients have expanded from natural products and low-molecular-weight compounds to peptides, proteins, antibodies, nucleic acids, and genome-editing molecules, requiring advanced and diverse pharmaceutical technologies or DDS. In particular, the evolution and development speed of biopharmaceuticals are extremely fast；however, the levels of required formulation and DDS technology are extremely high. Therefore, designing optimal formulation and DDS carriers for each API leads to stagnation in drug development. In this review article, we introduce our recent supramolecular carriers, termed as transformable polymers, with the ultimate goal of developing DDS carriers that can be applied to all biopharmaceuticals.
