1999 年 14 巻 1 号 p. 33-36
Electro-responsive on-off switching controlled release devices using solenoid for the actuator were prepared and the functions were tested. The devices were constructed from solenoid, bias spring and drug reservoir with an iron plate in a wan and a hole gate in the bottom. It was found that the drug reservoir moved by magnetic interaction according to input of electric current through the solenoid so as to fit the gate holes to cause the drug release from the reservoir. Then, the effects of magnetic flux density, moved distance of reservoir and number of nichrom wire coil on the on-off switching function were examined. The competent and compactness of solenoid were also improved. U shape solenoid and permalloy for solenoid core was used to increase the megnetic power. It was proved that on-off switching release of methylene blue as a model drug occurred quickly and sensitively with on-off switching of electromagnetic field in the device using the solenoid as the actuator.