抄録
A milk fat globule membrane (MFGM), which is the membrane components of cow milk derived from lactating mammary-gland cell, is mainly composed of both lipids and proteins. For the pharmaceutical usefulness of MFGM, the preparation of 5% triolein emulsions were studied by use of MFGM, in comparison with various surfactants ; lecithin, HCO60, Polysorbate 80. These emulsions were examined by two type methods of preparations which were homogenization alone (type A) and that following by sonication (type B). The mean diameters of oil droplets were determined by centrifugal lift method, and the emulsifiability was evaluated by turbidimetry. It was observed that the mean diameters of the emulsions by type B were smaller about one-third than those of emulsions by type A. The stability of emulsions by type B was also extensively improved. Furthermore, MFGM was suggested to have a strong emulsifiability as well as those of synthetic emulsifiers. These results indicate that MFGM can be substituted as natural emulsifier for synthetic emulsifier for oral use.
