The Japanese Journal of Dermatology
Online ISSN : 1346-8146
Print ISSN : 0021-499X
ISSN-L : 0021-499X
Original Articles
Five Cases of Symptomatic Primary HIV Infection
Mieko OiTomomi Tanese
Author information
JOURNAL RESTRICTED ACCESS

2011 Volume 121 Issue 5 Pages 857-862

Details
Abstract

We report five cases of symptomatic primary HIV infection. Four of the cases were MSM (men who have sex with men). They presented with a high grade fever lasting at least 3 days, lymphadenopathy, and sore throat. Erythema without pruritus was found on their trunks and extremities. They also had whitish spots on the buccal mucosa mimicking Koplick’s buccal spot or petechia on the hard palates. Results of blood tests showed cytopenia and liver dysfunction. HIV screening tests of the fourth generation showed slightly positive reactions. Levels of HIV-1 RNA in serum were very high, indicating the presence of acute HIV infection, even though anti-HIV-1 antibodies were not detected by Western blotting assays. Although the effects of antiretroviral therapy on primary HIV infection are not established, early detection of HIV infection is important so that treatment can be started at an appropriate point. Well-timed treatment can improve quality of life by avoiding the progression into AIDS and can prevent the infection from spreading.

Content from these authors
© 2011 Japanese Dermatological Association
Previous article Next article
feedback
Top