A Case of Congenital Hemangioma That Was Mostly Regressed by Lipoatrophy before Birth

Abstract

We report the case of a two year-old female infant who had had a slightly depressed lesion on the right lower abdomen which had an irregularly mixed pallor and dark red-colored erythema without local heat from birth. This lesion had remained unchanged for one year and eleven months since birth. Because it had remained unchanged in size and because the vascular endothelial cells were GLUT1 negative in immunohistochemical staining, we diagnosed her lesion as partially involuting congenital hemangioma (PICH) with lipoatrophy. The differential diagnosis was angioblastoma of Nakagawa (tufted angioma). Careful observation and GLUT1 stating in the immonohistochemical studies are important in diagnosing hemangioma in newborns and infants.