Myeloma-related Disorders (MRD) in Three Cats

Abstract

Three cats presenting with anemia were diagnosed with myeloma-related disorders by bone marrow examination. Bone marrow smears showed increased numbers of plasma cells, mainly proplasmacytes, in the first two cases and mature myeloma cells in the third case. All three cases were treated with melphalan and chlorambucil. The first two cats died on days 71 and 82, respectively, and the third cat died on day 288. Our results suggest that differentiation of plasma cell morphology using proplasmacytes and mature myeloma cells may provide a new prognostic indicator for myeloma-related disorders in cats.