Abstract
We met with a typical case of scleroderma generalisata, and found that dysfunction existed in the pituitary adrenal axis. Although injections of cortisone afforded only a temporary relief clinically, the transplantation of the cow-pituitary and the adrenal gland beneath the fascia lata bilaterally, improved both pituitary-adrenal function and subjective symptoms, especially the softening of the sclerosed skin and the alleviation of motorie disturbances were observed.
