Abstract
Wistar-Strain male rats were used in this experiment. The adrenal and parathyroid glands were studied morphologically and/or histochemically, and it was revealed that there were histochemical evidences of the hyperfunction of the adrenal glands in experimental hyperparathyroidism. Furthermore, the parathyroid glands were studied histologically in groups of rats with hypophysectomy, adrenalectomy, and parenteral administration with ACTH or cortison or DOCA, respectively. Serum calcium and inorganic phosphorus levels were determined in all of these groups. The function of the parathyroid glands was found to be decreaed remarkably in the hypohysectomized group, on the contrary, it increased in all of the other groups.
It has been concluded from the findings mentioned above that the parathyroid glands have a functional correlation with the adrenal glands and hypophyses, and it seems reasonable to postulate that calcium and inrganic phosphorus levels of the serum might play important roles in regulating such a functional relation between the parathyroid glands and the hypophyseo-adrenocortical system.
