A Case of Adrenocortical Cancer Treated with O, P'-DDD

NOBORU SAKAUCHI; SOICHI KUMAOKA; TSUGUO NARUKE; OSAHIKO ABE; MITSUTOSHI KUSAMA; OSAMU TAKATANI

doi:10.1507/endocrj1954.16.287

NOBORU SAKAUCHI, SOICHI KUMAOKA, TSUGUO NARUKE, OSAHIKO ABE, MITSUTOSHI KUSAMA, OSAMU TAKATANI

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JOURNAL FREE ACCESS

1969 Volume 16 Issue 2 Pages 287-290

DOI https://doi.org/10.1507/endocrj1954.16.287

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Abstract

O, P'-DDD was given to a 41-year-old Japanese woman with metastatic adrenocortical carcinoma with dosage of 8g a day orally. The treatment resulted in objective regression of all metastases for 237 days. Significant decrease was seen in ketosteroid, 17-hydroxycorticosteroid, 17-ketogenic steroids, estrogen in the urine, 17-hydroxycorticosteroid, cortisol in plasma during the course of treatment.

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