抄録
Ovulation was blocked by a single subcutaneous injection of chlorpromazine hydrochloride (CPZ) in the proestrous rat running 4-day estrous cycle under the controlled illumination (14L:10D). Ovulation inducing activities of various progestins including 4 newly synthesized compounds in this institute, were examined in these CPZblocked rats and compared with their endometrial proliferative activities in the rabbit.
Activities of endometrial proliferation in the rabbit, of ovulation induction in the rat, and of pregnancy maintenance in the rat were not always parallel in the progestins assayed.