Endocrine Journal
Our official Japanese journal "Naibunpigaku Zasshi" was first issued in 1925 and renamed as "Nihon Naibunpigaku-kai Zasshi" in 1927. In 1954 the first issue of English official journal "Endocrinologia Japonica" was published continuing to Volume 39 in 1992 and then renamed as the present "Endocrine Journal" from Volume 40 in 1993.

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収録数 6,598本
(更新日 2024/04/21)
Online ISSN : 1348-4540
Print ISSN : 0918-8959
ISSN-L : 0918-8959
2.0
2022 Journal Impact Factor (JIF)
ジャーナル 査読 オープンアクセス HTML 早期公開
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おすすめ記事
71 巻 (2024) 3 号 p. 295-303
Lung adenocarcinoma metastasis within a pituitary neuroendocrine tumor: a case report with review of literature もっと読む
編集者のコメント

Dr. Koji Suzuki and colleague report in the March issue an extremely rare case of metastatic lung adenocarcinoma within a gonadotroph pituitary neuroendocrine tumor (PitNET), representing a considerably expeditious progression of a variety of neurological symptoms. This excellent report provides us with invaluable insight into diagnosis and therapeutics for coexisting primary and metastatic tumors in pituitary gland.

71 巻 (2024) 2 号 p. 101-118
Single-cell and spatial transcriptomics in endocrine research もっと読む
編集者のコメント

As well known, endocrine organs including pituitary gland, adrenal gland and pancreatic islet of Langerhans et cetera consist of heterogenous cells, and pathophysiological interplay among hormone-producing cells and non-hormone-producing cells within tissue is crucial, at least in part, for molecular basis of a variety of endocrine diseases. In the February issue, Dr. Ryusaku Matsumoto and Takuya Yamamoto provide a comprehensive, fascinating review article focusing on the update of single-cell and spatial transcriptomics in endocrine research. Our editorial team has a firm belief that this review is a must-read for all dedicating clinicians and scientists on endocrinology.

71 巻 (2024) 1 号 p. 23-29
Clinical characteristics and potential biomarkers of thyroid and pituitary immune-related adverse events もっと読む
編集者のコメント

It is widely recognized that some cases of immune-related adverse events (irAEs) caused by immune checkpoint inhibitors (ICIs) result in life-threatening consequences including adrenal crisis and fatal diabetic ketoacidosis. In this issue, Dr. Tomoko Kobayashi and colleague contribute an insightful and well-organized review article on promising biomarkers to predict the onset of endocrine irAEs, particularly underscoring the mechanism-based management strategies and future prospect for pituitary and thyroid irAEs.

70 巻 (2023) 12 号 p. 1123-1130
Relationship between Ca2+ and cAMP as second messengers in ACTH-induced cortisol production in bovine adrenal fasciculata cells もっと読む
編集者のコメント

It is well known that both Ca2+ and cAMP play critical roles in ACTH-driven cortisol production by adrenal fasciculate cells. However, the division of role for Ca2+ and cAMP in this paradigm still remains obscure. In the December Issue, Dr. Masahiko Kutsukake and colleague elegantly unraveled such a long-standing enigma via sophisticated cellular experiments, demonstrating that cortisol production under steady state is preferentially mediated by Ca2+, but cAMP also participates under stressful conditions where ACTH demand is increased to adapt exaggerated stress.

70 巻 (2023) 10 号 p. 987-998
Prediction-based prompt levothyroxine replacement to prevent a hypothyroid state after immune-related adverse events involving the thyroid gland もっと読む
編集者のコメント

As well known, immune checkpoint inhibitors (ICIs) sometimes cause immune-related adverse events in the thyroid gland (thyroid irAEs). Dr. Ichiro Yamauchi and colleague conducted an elaborate retrospective cohort study demonstrating that patients with rapid-onset severe thyrotoxicosis as well as with positive TgAbs titers were highly likely to develop subsequent hypothyroidism. This study provides us with a message that expeditious replacement of levothyroxine is a crucial precaution against severely hypothyroid state.

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