抄録
1) Adult mongrel dogs, albino male rats, and human subjects were employed test the effect of Vasopressin and Oxytocin on the adenohypophysis. The experiments were carried out in three groups: Pitressin-injected, Pitocin-injected, and human urine Extract-injected groups.
2) By the injection of Pitressin, the pituitary-adrenocortical system is stimulated and the secretion of ACTH increases.
3) After the administration of human urine Extract, possessing a striking antidiuretic activity, similar changes as by the Pitressin injection occurs in the function of the pituitary-adrenocortical system.
4) Pitocin seems to increase the secretion of the gonadotrophic hormone, judged by the fractionations of urinary 17-ketosteroids and histological findings of adenohypophysis.
5) Brief discussions have been made on the concept that the anterior pituitary stimulated by the hypothalamic-pituitary neurosecretion.
