Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
Elevation of Serum 25-Hydroxycalciferol Levels in Androgen-Treated and Ultraviolet-Irradiated Rats
MASAHIRO OHATAYOSHIYUKI SAKAGAMITAKUO FUJITA
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1977 年 24 巻 5 号 p. 519-521

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Administration of 4-8 mg testosterone propionate significantly raised 25-hydroxycalciferol levels in the ultraviolet irradiated rats compared to the ultraviolet irradiated controls, but failed to influence serum 25-hydroxycalciferol levels in the non-irradiated animals. Estradiol benzoate and progesterone did not influence serum 25-hydroxycalciferol levels regardless of the ultraviolet irradiation. These findings implicate that testosterone enhances vitamin D biosynthesis induced by ultraviolet irradiation in rats, in accordance with the clinical observation that males often show higher levels of serum 25-hydroxycalciferol than females.
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© The Japan Endocrine Society
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