Further Studies on Gonadotropin-Inhibiting Substances Excreted in Human Urine
1977 年 24 巻 6 号 p. 545-550
詳細
1977 年 24 巻 6 号 p. 545-550
Partial separation of human urinary substances which have properties to suppress the ovulation induced by PMS and HCG in mice was attempted by gel filtartion on Sephadex G-100 and ultrafiltration using the Amicon Diafio membranes UM-2 and UM-10. In addition to a thermostable inhibitor which has a molecular weight more than 10, 000, the presence of a heat-labile inhibitor with a molecular weight less than 1, 000 was newly demonstrated.
