Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
The Effect of L-DOPA Administration on Thyrotropin (TSH) and Thyrotropin Releasing Hormone (TRH) Levels in Serum in Primary or Pituitary Hypothyroidism
TERUNORI MITSUMAYOSHIBUMI HIROOKASHUNMATSU WANIBENORIYUKI NIHEI
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1978 年 25 巻 5 号 p. 499-501

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The effect of acute administration of L-DOPA on TSH and TRH levels in serum was studied in primary or pituitary hypothyroidism. TRH levels in serum fell and then returned to initial levels after L-DOPA administration in primary or pituitary hypothyroidism. TSH levels in serum fell and then returned. to initial levels after L-DOPA administration in primary hypothyroidism. T4 and T3 levels in serum did not change after L-DOPA administration in primary or pituitary hypothyroidism. These data suggested that L-DOPA might act directly to hypothalamus.
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© The Japan Endocrine Society
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