Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
INFLUENCE OF pH ON THE THYROXINE EFFECT UPON SUCCINOXIDASE SYSTEM
MITSUO SUZUKIHIROO INOUEYUHSUKE SUGISAWAATSUSHI TAKAHASHI
Author information
JOURNAL FREE ACCESS

1956 Volume 3 Issue 2 Pages 98-105

Details
Abstract
1. D, L-thyroxine (final concentration: 1×10-4M) activates succinoxidase activity of mouse liver homogenate with addition of exogeneous cytochrome c, only in medium of narrow pH range around 7.4. Such effect of the hormone is not remarkable in pH 7.0 and 7.9.
2. No effect is found on the enzyme system with addition of L-diiodotyrosine and L-tyrosine in the same molar concentration with thyroxine (1×10-4M) at all pH employed.
3. From the data of spectrophotometric observation in ultraviolet region, solubility of thyroxine decreases with sharp gradient from pH 9 to 7.
Content from these authors
© The Japan Endocrine Society
Previous article Next article
feedback
Top