Absence of Effect of Estrogen on Dopamine, Norepinephrine and β-Endorphin-Like Immunoreactivity in Human Plasm

抄録

The plasma concentrations of immunoreactive norepinephrine (NE), dopamine (DA), β-Endorphin (β-E), luteinizing hormone (LH) and follicle stimulating hormone (FSH) were determined by RIA and HPLC every 6 h until 72 h after iv administration of conjugated estrogens during the midfollicular phase. The LH level showed a biphasic pattern after the injection of conjugated estrogens, i. e. significant suppression (-50%) for 6-42 h after the injection, followed by a rebound increase with a peak (+85%) at 72 h. The plasma levels of immunoreactive β-E, NE and DA did not change significantly for 72 h after the injection.