Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
A Circulating Thyroid Peroxidase-Like Substance in Healthy Human Peripheral Blood
TOMIO KOTANISACHIYA OHTAKI
著者情報
ジャーナル フリー

1988 年 35 巻 6 号 p. 849-855

詳細
抄録
Circulating thyroid peroxidase (TPO)-like substance in healthy human peripheral blood was studied to clarify the immunological role of TPO. By using a highly sensitive radioimmunoassay system combined with murine monoclonal antibodies, TPO-like substance was measurable in 6 out of 84 sera. Characterization of this circulating substance by gel filtration revealed that the molecular weight of a major peak corresponded to that of trypsinized TPO. From these findings it is possible that peripheral blood lymphocytes are exposed to a low level of TPO as well as to thyroglobulin.
著者関連情報
© The Japan Endocrine Society
前の記事 次の記事
feedback
Top