抄録
The central mechanism controlling food intake in response to the change in environmental temperature has been little examined. The GABA agonist, muscimol, was injected into the lateral ventricle of rats which were acclimated to temperate (26°C) and hot (33°C) environments. Muscimol obviously stimulated the feeding behavior of rats in both environments. However, when muscimol was administered at doses of 100 and 250ng, the food intake at 26°C was greater than that at 33°C. In addition, the stimulating effect of muscimol (250ng) on food intake at 26°C lasted longer than that at 33°C. These findings suggested that there might be a difference in muscimol metabolism at the two temperatures.
