URINARY EXCRETION OF STEROIDS OF ALLOPREGNANE-TETROL AND-PENTOL TYPES

Abstract

The study was made on the quantitative estimation of steroids of allopregnanetetrol and-pentol types, excreted in urine.
1) The urinary excretion of the aimed steroids amountcd to 1.6-10.0mg per day in healthy adults.
2) The administration of ACTH or hydrocortisone showed marked increases in their daily excretion. When 50-100mg hydrocortisone was administered, ca.
9.3-18.7mg was excreted as steroids of allopregnane-tetrol and-pentol types and 8.2-32.6mg as steroids of allopregnane-17, 21-dio1-20-one type respectively.