抄録
1. Effect of serotonin on blood lactate level of rats were examined.
2. Serotonin, administered intravenously, subcutaneously or intraperitoneally, caused a rise of blood lactate.
3. Effectiveness of serotonin in causing hyperlactacidemia was far more than that of epinephrine if considered on the basis of physiological concentration in circulation.
4. Serotonin had no effect on blood glycolysis both in vivo and in vitro.
5. The possibility that serotonin may act primarily on carbohydrate metabolism in peripheral and/or hepatic tissues are discussed.
