抄録
(A) 1. Parotin administration affected both the exocrine and endocrine pancreases of mice.
2.β cells seemed increased and islets were larger and more numerous in the treated mice.
3. Serum glucose was depressed after parotin was given.
4. Ductal epithelium showed proliferation and increased cellularity in the experimental animals.
5. Vascularity was increased in both the exocrine and endocrine pancreases where parotin was given.
6. Adrenals showed increased vascularity and Zone X near the medulla had more cells and was wider in treated animals.
(B) 1. There was better survival of anterior chamber guinea pig homotransplants of fetal pancreatic tissue when parotin was given.
2. Vascular increases to the transplants was observed soon after each parotin injection.
3. Pancreatic islet tissue was more definitive histologically in parotin injected hosts.
4. Cystic formations were more pronounced in the non-treat control host.
5. Ducts appeared to be more functional in the treated hosts.
6. The exocrine in situ pancreatic tissue of treated hosts showed a difference in gross appearance and histologically there were unusually high areas of fat cells.
