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Experimental Animals
Vol. 46 (1997) No. 4 P 287-290

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http://doi.org/10.1538/expanim.46.287

Original

The effects of Eurycoma longifolia Jack were studied on the libido of sexually experienced male rats after dosing them with 200, 400 and 800 mg/kg body weight twice daily of different fractions of E. longifolia Jack for 10 days. Results showed that E. longifolia Jack produced a dose-dependent increase in mounting frequency of the treated animals with 400 mg/kg of chloroform, methanol, water and butanol fractions resulting in mounting frequencies of 5.3 ± 1.2, 4.9 ± 0.7, 4.8 ± 0.7 and 5.2 ± 0.1, and 800 mg/kg further increased them to 5.4 ± 0.8, 5.4 ± 0.8, 5.2 ± 0.6 and 5.3 ± 0.2 respectively but there were no erections, intromissions, ejaculations or seminal emissions during the 20-min observation period which allowed for the measurement of sexual arousal reflected by mounting frequency uninfluenced by other behavioural components. This study provides evidence that E. longifolia Jack is a potent stimulator of sexual arousal in sexually vigorous male rats in the absence of feedback from genital sensation.

Copyright © 1997 Japanese Association for Laboratory Animal Science

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