Experimental Animals
Online ISSN : 1881-7122
Print ISSN : 1341-1357
ISSN-L : 0007-5124
Eurycoma longifolia Jack Enhances Libido in Sexually Experienced Male Rats
Hooi Hoon ANGMeng Kwoon SIM
ジャーナル フリー

1997 年 46 巻 4 号 p. 287-290


The effects of Eurycoma longifolia Jack were studied on the libido of sexually experienced male rats after dosing them with 200, 400 and 800 mg/kg body weight twice daily of different fractions of E. longifolia Jack for 10 days. Results showed that E. longifolia Jack produced a dose-dependent increase in mounting frequency of the treated animals with 400 mg/kg of chloroform, methanol, water and butanol fractions resulting in mounting frequencies of 5.3 ± 1.2, 4.9 ± 0.7, 4.8 ± 0.7 and 5.2 ± 0.1, and 800 mg/kg further increased them to 5.4 ± 0.8, 5.4 ± 0.8, 5.2 ± 0.6 and 5.3 ± 0.2 respectively but there were no erections, intromissions, ejaculations or seminal emissions during the 20-min observation period which allowed for the measurement of sexual arousal reflected by mounting frequency uninfluenced by other behavioural components. This study provides evidence that E. longifolia Jack is a potent stimulator of sexual arousal in sexually vigorous male rats in the absence of feedback from genital sensation.

© 1997 Japanese Association for Laboratory Animal Science
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