Experimental Animals
Online ISSN : 1881-7122
Print ISSN : 1341-1357
ISSN-L : 0007-5124
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Characterization of a Novel Polycystic Kidney Rat Model with Accompanying Polycystic Liver
Makoto KATSUYAMATakeshi MASUYAMAIchiro KOMURATsutomu HIBINOHisahide TAKAHASHI
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JOURNAL FREE ACCESS

2000 Volume 49 Issue 1 Pages 51-55

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Abstract

A polycystic kidney rat model is being established from a Crj:CD (SD) rat strain. Unlike existing animal models of polycystic kidney disease, this mutant rat has a completely polycystic liver. Mating experiments revealed that the phenotype is controlled by an autosomal recessive gene. We propose that this gene be tentatively called the "rpc" gene.

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© 2000 Japanese Association for Laboratory Animal Science
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